Variables

>1% weight loss N = 779 loss, 731 gain

>3% weight loss N = 491 loss, 731 gain

>5% weight loss N = 319 loss, 731 gain

Odds ratio (95% CI)

p-value

Odds ratio (95% CI)

p-value

Odds ratio (95% CI)

p-value

Weight loss vs. gain

2.22 (1.32, 3.73)

0.003

2.96 (1.65, 5.31)

<0.0001

3.31 (1.69, 6.47)

<0.0001

Age

1.01 (0.98, 1.03)

0.58

1.01 (0.98, 1.04)

0.58

1.01 (0.98, 1.04)

0.49

Male vs. female

0.88 (0.49, 1.57)

0.66

0.83 (0.44, 1.58)

0.57

0.87 (0.44, 1.71)

0.68

Education: college vs. high school

1.52 (0.88, 2.64)

0.13

1.66 (0.91, 3.03)

0.10

1.59 (0.84, 3.02)

0.15

Education: graduate vs. high school

1.02 (0.42, 2.52)

0.96

1.16 (0.43, 3.12)

0.77

1.06 (0.34, 3.28)

0.92

Cancer

0.64 (0.32, 1.28)

0.21

0.40 (0.18, 0.90)

0.026

0.62 (0.26, 1.48)

0.28

Cholesterol problems

1.04 (0.56, 1.92)

0.90

0.79 (0.40, 1.54)

0.49

0.84 (0.42, 1.66)

0.61

COPD

1.40 (0.55, 3.54)

0.48

2.31 (0.77, 6.87)

0.13

1.69 (0.55, 5.18)

0.36

Heart disease/heart attack

0.92 (0.50, 1.69)

0.78

0.71 (0.35, 1.43)

0.34

0.92 (0.44, 1.96)

0.84

Stroke/TIA

0.70 (0.22, 2.17)

0.53

0.43 (0.12, 1.57)

0.20

0.53 (0.14, 2.02)

0.35

Weight at baseline

0.992 (0.987, 0.997)

0.003

0.991 (0.986, 0.997)

0.003

0.99 (0.986, 0.998)

0.011

PHQ-9 at baseline

1.30 (1.22, 1.40)

<0.0001

1.28 (1.19, 1.38)

<0.0001

1.26 (1.16, 1.35)

<0.0001